Eyes Closed to Fingers Crossed picks up on Santana shortly after "Sexy", and departs from Glee canon from that point onwards. Note: this series is not Brittana. Mind the pairings listed in the series.
The series follows Santana for the next 3 years and covers, loosely, her coming out process in junior year of high school (Five Stages), her last year of high school and her hang-up on Brittany (The Lights That Stop Me), her freshman year of college in New York, in which she tries to move on with her life (Blind With Casualties), and her sophomore year in college, during which time she actually moves on (We Started Secret Plans).
The main is separated by interludes from other people's perspectives and concluded with an epilogue set in 2019.