The year is 2976. Aaron Burr is an extraordinary scientist at Leigh Co., one of the top researching companies in current day America. It is currently owned by the near-aristocratic Yamaguchi family, one of few that own and operate (publicly) peacefully in New York. One day, Burr is pulled away from his current work on the company's long-awaited and very costly antidepressant by Mr. Yamaguchi himself (who rarely interacts with company scientists.) Mr. Yamaguchi presents him with something horrifying: a pill and a person.
Burr is given an offer: work on a new (extremely illegal) drug for "the good of the company", or never be seen or heard from again.