dean and cas go through tragedies together
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Dean's family is killed in a house fire when he was eight.
Castiel's family was killed in a car accident when he was ten.
Both boys blame themselves.
Stuck at the same hospital, and later the same foster care, they have no choice but to become friends, especially because they are roommates.
Through the years, the boys became close friends, best friends, until suddenly they were more.
That is until Castiel disappeared.
Now, years later, a serial killer by the name of Morningstar is making headlines, and Dean knows it's Castiel.
Or the story when Dean falls in love with a serial killer.