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For a prompt from Fascinationex: “ninja are meant to be able bodied, but plenty of them grow to experience chronic injuries and illnesses due to the nature of their work. exposure to poisons and dodgy joints are common, for example. a lot of medicine and man hours go into keeping good ninja in working order -- but when a ninja becomes a missing-nin, she starts having to deal with these problems independently. and that's when problems arise.”
In Mist, you fought until you couldn’t, and then you got a desk job. Unfortunately “desk job” doesn’t translate well into “missing-nin.”