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Dean, feverish and unsteady since he touched the First Blade, collapses in the middle of the hunt for Abaddon. Sam calls on Castiel, who can tell them only that something is very wrong with Dean’s soul—and that the other angels can sense it. As the Mark of Cain grows bigger and uglier and his dreams get weirder, an increasingly sick and pissed-off Dean chafes against Castiel’s hands-on brand of concern and his strained relationship with Sam.
Kevin, meanwhile, may be dead, but he and his mother have a plan anyway, and Dean might be the guy to make it happen.