Aaron Taylor-Johnson as Prof. Norville "Shaggy" Rogers
THE HEX GIRLS:
Megan Fox as Sally McKnight/Thorn
Michelle Trachtenberg as Muffy St. James/Dusk
Eliza Dushku as Kimberly Moss/Luna
JOSIE AND THE PUSSYCATS:
Katherine McNamara as Josie McCoy
Selena Gomez as Melody Valentine
Cymphonique Miller as Valerie Brown
JEM AND THE HOLOGRAMS:
Gwen Stefani as Jerrica Benton/Jem
Jamie Lynn Spears as Kimber Benton
Brenda Song as Aja Leith
Fefe Dobson as Shana Elmsford
Christina Aguilera as Carmen "Raya" Alonso
Edward Speleers as Archie Andrews
Andrew Garfield as Jughead Jones
Taylor Lautner as Reggie Mantle
Lindsay Lohan as Veronica Lodge
Allison Mack as Betty Cooper
Glen Powell as Milo
Ellington Ratliff as Simon
ALVIN AND THE CHIPMUNKS:
Justin Long as Alvin
Matthew Gray Gubler as Simon
Jesse McCartney as Theodore
Jason Lee as Dave Seville
Christina Applegate as Brittany
Anna Faris as Jeanette
Amy Poehler as Eleanor
Slash as Nathan Explosion
Mikael Åkerfeldt as Skwisgaar Skwigelf
Trey Azagthoth as Toki Wartooth
King Diamond as William Murderface
Chris Barnes as Pickles
Jim Sturgess as Stuart Pot/2D
Hugh Jackman as Murdoc Niccals
Ice Cube as Russell Hobbs
Jing Tian as Noodle/Asuka Ōkuma
Will Smith as Del Tha Ghost Rapper
Charlize Theron as Cherry
DJ Dyna Mink
Gary Oldman as Kerry McCall, the host of the competition.
Orlando Bloom as Rio Pacheco, Jem's boyfriend and childhood friend who is the band's road manager and engineer.
Jennifer Lawrence as Alexandra Cabot, rival of Josie and the Pussycats who is a spoiled, selfish and hot-tempered girl with no talent.
Armand Assante as Eric Raymond, a greedy and arrogant music executive and CEO of Starlight Music and the Misfits' manager.
Avril Lavigne as Pizzazz, lead singer of The Misfits who is the enemy of Jem and the Holograms who has a thing for Rio.
Zach Braff as David, a young chipmunk who is Brittany's new boyfriend after her relationship with Alvin hit a snag.
Leigh Whannell as Jack Cartwright, a nature photographer and Noodle's fiancee.